subject treatment t1 t2 t3 t4 1 bt 1.5 9.0 5.0 4.0 2 bt 5 14 4.5 7 3 bt 1 8 4.5 2.5 4 bt 5 14 8 5 5 bt 3 8 4 4 6 bt 0.5 3.5 1.3 1 7 bt 0.5 3 1 0 8 ro 2 5 5 1.5 9 ro 1.5 1.9 1.5 1.0 10 ro 3.5 7 8 4 11 ro 1.5 4.2 2 1.5 12 ro 1.5 3.6 2 1 13 ro 1.5 2.5 2.8 4 14 ro 1.5 2.4 0.5 0.0 15 ctrl 3 3.1 0.5 2 16 ctrl 5 4.3 3.5 4.0 17 ctrl 1.5 0.8 1.3 3 18 ctrl 2 2.6 1.5 2 19 ctrl 6 3.5 4 3 20 ctrl 1 1 0.3 0 21 ctrl 0 0.3 0.3 1